By Randolph Howes
The NMR has the top point of oxidative pressure of all rodents and it lives 8 instances so long as different rodents, with an excellent healthspan and it hasn't ever had a case of melanoma stated during this species….ever!
What does the bare mole rat and workout have in universal that may revolutionize our pondering oxygen, electronically changed oxygen derivatives (EMODs) and oxidative metabolism?
Are oxygen unfastened radicals or reactive oxygen species the mobile assassins they've been portrayed to be? Or, may they be the key weapon of the NMR which retains it in sturdy overall healthiness for thus long?
Is there a commonality among the NMR and the consequences of elevated oxygen intake and so-called oxidative pressure linked to exercise?
Can the original salutary advantages of workout and specified EMOD features be utilized to guy, such that our healthspan is dramatically prolonged, in addition to our lifespan?
The hallmark of workout is a 10-20% raise in oxygen intake, that's speedily metabolically switched over to electronically changed oxygen derivatives, EMODs (EMODs, previously confusingly known as reactive oxygen species, ROS).
Can over the top degrees of supplemental antioxidants and antioxidant supplements block or intrude with some great benefits of exercise?
Is "exercise deficiency disorder" comparable to an "EMOD insufficiency disease?" EMOD and workout insufficiency "allows" ailments to appear themselves similar to melanoma, center sickness, strokes and arthritis.
I think that oxygen metabolomics seem to be the root of the nice healthiness and sturdiness noticeable within the NMR and within the merits linked to workout. Oxygen and its EMOD progeny is the purpose of convergence for workout and the bare mole rat, because it pertains to healthspan and lifespan.
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